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Ulcerative Colitis Accompanied by Duodenitis, Report of Two Cases Ritsuko Fujisawa 1 , Takayuki Matsumoto 1 , Shotaro Nakamura 1 , Hideki Koga 1 , Shinichiro Yada 1 , Motohiro Esaki 1 , Yutaka Ouji 2 , Takashi Yao 2 , Ryuichi Mibu 3 , Mitsuo Iida 1 1Departments of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan 2Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan 3Department of Surgical Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan Keyword: ulcerative colitis , duodenitis pp.505-512
Published Date 2007/4/25
DOI https://doi.org/10.11477/mf.1403101027
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 〔Case 1〕was a 29-year-old female with abdominal pain. She had been diagnosed as ulcerative colitis (UC) of pancolitis type and treated by total proctocolectomy 10 years previously. Esophago-gastro-duodenoscopy (EGD) showed ulcers and coarse, granular mucosa in the duodenal bulb and in the second portion of the duodenum. Although she was treated with ranitidine and 5-aminosalicylic acid (5-ASA) for 18 months, her duodenal lesions remained unchanged.

 〔Case 2〕 was a 69-year-old male with a history of UC for 4 months. EGD revealed multiple ulcers in the duodenal bulb and in the second portion of the duodenum. Under treatment with prednisolone and 5-ASA, his duodenal lesions, as well as UC, markedly improved. Our cases suggest that duodenal involvement of UC, referred to as “ulcerative duodenitis”, shows a heterogeneous clinical course as seen in its colonic involvement.


Copyright © 2007, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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