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- Abstract 文献概要
- 1ページ目 Look Inside
I．結言
現在皮膚萎縮症という分類に属するものには非常に多数の疾患が含まれている。しかしその分類はもつぱら臨床的ないし組織学的に行なわれているのが現状であり，その発生機序には不明な点が多く，又臨床的，組織学的に皮膚萎縮症と考えられてもこれらの分類中いずれに属せしめうるか迷う症例に遭遇することがまれではない。われわれは最近，父と息子にみられた先天性ならびに遺伝性と考えられる一種の皮膚萎縮症例を経験したので以下にその大要を報告する。
Two cases of aplasia cutis congenita circumscripta in a boy and in his father were reported, which were considered inherited dominantly and had benign prognosis.
Case 1 : A 2 year and 6 month-old boy had at birth atrophic maculae on the bilateral temples. At his first visit the areas were symmetrically studded with a some, round, nail-sized, slightly depressed atrophic maculae simulating scars with brown pigmentation.
Histologic specimen showed the slightly atrophic epidermis, dermis and skin appendages. Otherwise they were almost normal.
Case 2 : A 37 year-old man, father of case 1, had a few, round, up to 5 mm in diameter, atrophic maculae in groups around the outer canthi of the both eyes. This patient's father was stated to have the same skin manifestations above mentioned.
In both cases, there were several deep furrows running sagitally in the midline of the fore-head. A relation between those furrows and the atrophic spots was undetermined. No abnormal findings were obtained in the bones and other organs.
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