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Clinical implication of diurnal intraocular pressure curve in low tension glaucoma Reiko Ishii 1 , Junkichi Yamagami 1,2 , Makoto Araie 1 1Dept of Ophthalmol Tokyo Univ Sch of Med 2Dept of Ophthalmol Tokyo Metropolitan Geriatric Hosp pp.1445-1448
Published Date 1990/9/15
DOI https://doi.org/10.11477/mf.1410900358

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  • Abstract
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We evaluated the clinical value of 24-hour-around-the-clock intraocular pressure (IOP) mea-surement in 118 eyes of 60 patients suspected of low tension glaucoma (LTG). The findings were compared with IOP readings in the outpatient clinic (out-IOP) in the same group. Seven eyes in 4 cases manifested IOP readings of 22mmHg or higher by 24-hour IOP measurement and were excluded from the LTG group. These 4 patients showed mean I0P of 17.8±1.5mmHg, which was significantly higher than that in the remaining 56 LTG patients, 15.5±1.3mmHg (p<0.01). In the LTG group, the out-IOP was significantly higher than the 24-hour I0P regarding the peak, the trough and the mean by 0.8±1.9, 1.1±1.7 and 1.2±1.3mmHg, respectively (p<0.001). The correlation coefficients between the out-I0P and 24-hour IOP (r) were 0.58 for the peak, 0.65 for the trough, and 0.79 for the mean, respectively. Furthermore, the mean IOP in the outpatient clinic was also significantly higher than the mean 24-hour IOP by 1.2±1.4mmHg (p<0.001, r=0.60). The ordinary IOP in LTG cases fluctuated at a level higher by 1mmHg than the estimated value by 24-hour IOP measurement. This finding seemed to be of clinical significance in deciding the modality of treatment for LTG.


Copyright © 1990, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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