何らの脱落症状なく極めて長い経過をとれる側頭頂葉Glioblastoma multiformeの1例について

On a Case of Left Parietal Glioblastoma Multiforme with a Long Course Presenting no Local Sign

　Glioblastoma multiforme （以下G.　M.と略す）の中にも少数ながら経過の長いもののあることは，Cushing and Bailey^1）も夙に指摘したところであり，しかもその後の観察，研究が進むにつれて，この経過の長い云わば比較的良性のものが以前考えられていた程少ないものではないことも解つてきた。そこで欧米に於いては，G．M．を更に2つ乃至3つの亜型に分ける種々の試みがなされてきた。例えばfibril formationとMitosisから三型に分つDeery^2）の試み，壊死の程度によりprimary typeとsecondary typeに分つScherer^3）の試み，或いはangionecrotic, mul-ticellular及びmagnocellularの三つの亜型に分つBusch and Christensen^4）の法，更にAngiothrombotic gropu　と　angioproliferativegroup　とに分つDavis et al^5）の分類法等があり，お互のgroupの間にその臨牀経過の上で著明な差を見出している。

A boy of fifteen had a five-year history of Jacksonian convulsive seizures which were found to result from glioblastoma multiforme which chiefly invaded the left parietal lobe. This tumor was cystic, evacuated by opera-tion and then irradiated. Since these treat-ments, he has present no neurological deficit and also no epileptic attack for three years and eight mounths. He is now leading quite a normal life.

Microscopically, this case was characte-rized by a relatively poor density of cells, less frequent appearance of mitotic figures and a slight proliferation of the wall of the blood vessels except for hemorrhage.

In other words, polymorphism was not striking though a number of giant cells was moderate.

It was interesting that the course was pro-longed and such a local sign as aphasia, apraxia, and also agnosia was not observea, though the tumor was found to be gliobla-stoma multiforme microscopically and so large a tumor as a small fist occupied the left parietal lobe of the dominant hemis-phere.