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The distribution of pulmonary perfusion and ventilation in mitral stenosis with extreme pulmonary hypertension Naohiko Kurata 1 , Yoshihiro Takeuchi 1 , Tsutomu Ooi 1 , Tamotsu Morimoto 1 , Masanori Kaneda 1 , Shinya Miyake 1 , Humio Kitamura 1 , Shoji Namikawa 1 , Hiroshi Yuasa 1 , Minoru Kusagawa 1 1The Department of Thoracic Surgery, Mie University School of Medicine pp.1339-1345
Published Date 1983/12/15
DOI https://doi.org/10.11477/mf.1404204361

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  • Abstract
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The purpose of this study is to investigate the changes of regional distribution of pulmonary perfusion and ventilation in mitral stenosis with extreme pulmonary hypertension (mPAP<4040 mmHg) following surgical treatment. For the assessment of the regional perfusion and ventilation using Xe-133, perfusion index and ventilation index which mean the perfusion and ventilation per unit lung volume, have been calculated using scintilation camera-on line computer system.

The results are summarized as follows.

1. Ten patients have been studied.2. There were two types of distribution of pulmonary perfusion. Type A showed the inverted distribution of normal distribution of pulmonary perfusion, as well known according to the many past reports. Type B showed the distribution uniform throughout the lung. 3. The patients with type B had severe pulmonary vascular resistance and abnormal distribution of ventilation. 4. Postoperatively, the distribution of pulmonary perfusion in type A returned to normal after 6-12 months of surgical treatment, but in the type B never returned to normal even after 12 months of surgical treatment. 5. In hemodynamic datas after 3-6 months of surgical treatment, the patients with type B showed the moderate pulmonary hypertension and pulmonary vascular resistance. 6. The abnormal distribution of ventilation in patients with type B improved in normal distri- bution after 12 months of surgical treatment. 7. In conclusion, perfusion index and ventilation index are very beneficial to estimate the pulmo- nary hypertension in mitral stenosis with or without high pulmonary vascular resistance before surgical treatment, and these two indices are good markers to estimate the improvement of regional pulmonary perfusion and ventilation along with the improvement of hemodynamic datas after surgical treatment.


Copyright © 1983, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1200 印刷版ISSN 0452-3458 医学書院

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