X線上逆追跡可能であった食道癌の2例

Retrospective Study on Growth of Esophageal Cancer Based on Radiographic Findings, Report of Two Cases

要旨　X線上逆追跡可能であった食道癌の2例を報告した．〔症例1〕はX線検査で中部食道に長さ2.8cmの不整な顆粒状粘膜を認め，16か月後には辺縁の欠損と不整な隆起性病変（4.3×2.0cm）に変化した．doubling time（DT）は8.6か月であり，経過中に長径を増し，発育は速かった．〔症例2〕では食道中部に辺縁不整のⅡa様隆起（長さ2.4cm）が認められ，21か月後には主病変部の長径は明らかな増加を示さず，横径が増加し，口側に2個の壁内転移を生じた.DTは31.4か月で，発育速度は緩やかであった．2例は共に隆起型であり，初期病変はX線上顆粒ないし結節様陰影として描出され，相似増大型の発育を呈した．

　We reported two cases of patients with esophageal cancer who had undergone x-ray examinations more than one year before the diagnosis. These radiographic findings were analyzed retrospectively. In the first case, a fine granular elevation measuring 28 mm in diameter developed into a cancer measuring 43 mm in diameter, which was superficial and protruded type. The doubling time was estimated to be 8.6 months during the observation period of 16 months. Histologic finding of the resected specimen revealed moderately differentiated squamous cell carcinoma invading the submucosa.

　In the second case, a flat elevation with nodularity measuring 24 mm in diameter developed into a cancer measuring 28 mm in diameter, which was superficial and protruded type with two distant intramural metastases. The doubling time was estimated to be 31.4 months during the course of 21 months. Histologically, the lesion was poorly differentiated squamous cell carcinoma invading the submucosa.