4年3ヵ月の間に小異型上皮巣からBorrmannⅠ型進展癌になったと思われる1症例

Small Atypical Epithelium of the Stomach Developing into Advanced Carcinoma of Borrmann Type Ⅰ in the Course of Four Years and Three Months, a Case Report

　岡部が提唱した胃癌のRetrospective follow up studyは，胃癌の発育進展過程を考察する上の有力な武器となることは周知の通りである．

　しかし，隆起性病変の発育進展過程に関しては異型上皮巣と胃癌との鑑別診断が確立されていないために，retrospectiveなX線，内視鏡所見の推移のみからは，異型上皮細胞腫が胃癌へと進展したのか，あるいは最初から癌であったものが大きくなるのか，解釈できないことが多い．

　1. Of two coexisting protrusions of the stomach, one, at first measuring only 8 by 5 mm, grew up to advanced carcinoma as large as 40 by 35 mm in the course of four years and three months.

　2. This tumor had been biopsied twice during its development. We cannot help thinking that a Ⅱa-like protrusion with lower degree of atypicality has later developed into advanced carcinoma with increasing atypicality.

　3. The coexisting other protrusion (atypical epithelium of intestinal type) has hardly changed its shape all through this long period.