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Clinical Study of Metachronous Multiple Primary Carcinomas of the Large Bowel Yoshiki Usui 1 , Tokiko Yamaguchi 2 , Junichi Iwadare 1 , Rikisaburou Sahara 1 , Tetsuya Okuda 1 1Social Insurance Central Hospital Coloproctology Center 2Marigold Clinic Keyword: 異時性多発大腸癌 , 多発大腸癌 , 大腸癌 , サーベイランス , 大腸内視鏡検査 pp.1027-1030
Published Date 2000/7/25
DOI https://doi.org/10.11477/mf.1403104759

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  • Abstract
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 For 38 years from 1961 to 1998, 75 cases with metachronous multiple primary carcinomas of the large bowel were diagnosed, polypectomized or/and operated on at our center. The 75 cases of metachronous multiple primary carcinomas accounted for 2.4% out of a total of 3,149 cases (3,542 lesions). The mean age was 62.1 years. Forty nine patients were men, and 26 were women, a ratio of 1.88 to 1. The metachronous multiple primary carcinomas were mostly found in cases where there was a combination of advanced cancer and early cancer. Compared with the incidence of single carcinomas, metachronous carcinomas were most likely to be located in the right colon. The average interval between the first and second carcinomas was six years ranging from one year to as long as 26 years. The distribution of the occurrence period showed two peaks: three years or less (at a relatively early stage) and longer than five years. Periodical colonoscopy should be undertaken one year after operation and polypectomy and even up to five years after the original treatment.


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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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