小児Langerhans cell histiocytosis（LCH）の2例

・Langerhans cell histiocytosis（LCH）は病変部位と病変数による分類が近年頻用されており，自験例では症例1と症例2で異なる分類，治療方針となった．

・症例2は皮疹からLCHの診断に至った症例であり，まれな疾患ではあるものの，小児の難治性皮疹をみた場合，鑑別としてあげるべきと考えた．

（「症例のポイント」より）

　

Two cases of infantile Langerhans cell histiocytosis

　

Nakagawa, Tomoe1）Hori, Masako2）Kanno, Kyoko2）Yamamoto, Akemi2） 1）Department of Dermatology, Nayoro City General Hospital 2）Department of Dermatology, Asahikawa Medical University

　

We report two cases of Langerhans cell histiocytosis (LCH). Case 1： A seven-month-old girl was admitted to our hospital with a pre-auricular tumor and purpura on chest. Histopathologic examination revealed a proliferation of Langerhans cells. A diagnosis of LCH was made. These symptoms remitted with a combination therapy. Case 2：A six-month-old boy presented with papules, purpura, and depigmentation on the face and trunk. Histopathological examination revealed an increased number of histiocytic cells in the epidermis and the papillary dermis. The patient was diagnosed with LCH and the lesions resolved spontaneously.