Volume 29, Issue 1 (December 2018)

Calcium Metabolism and Skeletal Changes during Pregnancy and Lactation. Yasuda Shun 1 , Mizunuma Hideki 2 1Department of Obstetrics and Gynecology, Iwase General Hospital, Fukushima, Japan. 2Fukushima Medical Center for Children and Women, Fukushima Medical University, Fukushima, Japan. pp.19-26
Published Date 2018/12/28
DOI https://doi.org/10.20837/4201901019
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 Calcium metabolism changes dramatically during pregnancy and lactation because offspring needs a supply of calcium. Approximately 30g of calcium, which passes through the placenta, is accumulated in a fetus during pregnancy mostly in the third trimester, and 220-340mg/day of calcium is supplied via breast milk during lactation. However, there are elaborate mechanisms to maintain maternal calcium homeostasis, which differs during pregnancy and lactation. Extra required calcium supply to the offspring in neither pregnancy nor breastfeeding normally do not cause any adverse consequences to the maternal skeleton even if any oral intake of calcium or vitamin D are increased.  This article reviews the adaptation in calcium kinetics during pregnancy and lactation. Vitamin D, calciotropic hormones, and bone metabolism are also reviewed.


29巻1号 (2018年12月)
電子版ISSN 印刷版ISSN 0917-5857 医薬ジャーナル社