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Stem Cell System. Hair follicle stem cells. Sawatsubashi Shun 1 1Department of Molecular Endocrinology, Fujii Memorial Institute of Medical Sciences, Institute of Advanced Medical Sciences, Tokushima University, Japan. pp.803-808
Published Date 2017/5/28
DOI https://doi.org/10.20837/4201706033
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 The hair follicle is a complex miniorgan of the skin and undergoes cycles of growth(anagen), apoptosis-mediated regression(catagen)and rest(telogen). Regeneration of the new hair shaft dependent on the activation of hair follicle stem cells(HFSCs), harboured in the bulge region. Using a hair follicle model, some molecular players that control the balance between HFSC maintenance and ageing-associated HFSC dysfunction have been identified. Here, we reviewed and discussed the recent findings of molecular characterization of HFSCs biology and pathology.



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電子版ISSN 印刷版ISSN 0917-5857 医薬ジャーナル社

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