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Treatment of Bone Diseases in ESRD Patients. Bone turnover and mineralization in patients with kidney failure. James Junichiro 1 1Department of Nephrology and Hypertension, Fukushima Medical University, Japan. pp.1261-1267
Published Date 2016/8/28
DOI https://doi.org/10.20837/4201609017
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 Bone remodeling is a device to accomplish "the buffering of the extracellular fluid mineral", which is one of the two major physiological functions of bone. Bone turnover is a term to express the frequency of bone remodeling, and its last step is calcification. When remodeling is induced, at first a large amount of mineral is released from bone to extracellular fluid transiently, and thereafter mineral is slowly and steadily drawn into bone. The extracellular minerals, especially calcium, are maintained by this repetition. When kidney is injured, bone turnover takes a wide spectrum from remarkably high cases to low cases. Primary calcification also shows marked individual differences. The classic renal bone diseases 5 classification clearly categorizes these disease condition, which is synonymous with renal osteodystrophy today.



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電子版ISSN 印刷版ISSN 0917-5857 医薬ジャーナル社

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