雑誌文献を検索します。書籍を検索する際には「書籍検索」を選択してください。

検索

書誌情報 詳細検索 by 医中誌

Japanese

Development of Tazobactam and Piperacillin for injection-TAZOPIPE R Combination for I.V. Infusion「Meiji」to satisfy medical needs- Kaneshige Junichi 1 , Takahashi Michiko 1 , Ota Kazumi 2 , Kai Natsumi 1 , Nakazawa Daisuke 3 , Tsushima Masaki 1 , Fujita Michinari 1 1Meiji Seika Pharma Co., Ltd. Chemistry, Manufacturing & Control Research Laboratories 2Meiji Seika Pharma Co., Ltd. Generics Planning & Promotion Department 3Meiji Seika Pharma Co., Ltd. Production Technical Department, Production Division Keyword: タゾピペ(注射用タゾバクタム・ピペラシリン) , 後発医薬品 , 医療ニーズ , 原薬 pp.154-163
Published Date 2017/6/25
DOI https://doi.org/10.20837/2201707154
  • Abstract
  • Look Inside
  • Reference

 TAZOPIPE R Combination for I.V. Infusion「Meiji」is the generic drug(freeze-dried formulation)of Zosyn for I.V. Infusion that is a mixed product of Piperacillin, a penicillin antibiotic with broad spectrum, and Tazobactam, a β-lactamase inhibitor. Medical needs survey conducted prior to development of this generic drug revealed high expectations for smaller vials and packages, improved solubility, and devices to avoid a risk of misidentifying the drug. As the result of endeavor to satisfy these demands, we succeeded in miniaturizing the product, while keeping good solubility. Moreover, we selected high-quality drug substances and devised improvements to the packaging to avoid confusions. Finally we succeeded in creating high-quality, user-friendly and highly-valued product with the original efficacy, which fully meets medical needs.



基本情報

電子版ISSN 印刷版ISSN 0913-2384 医薬ジャーナル社

関連文献

もっと見る

文献を共有