思春期早発症を主訴に発見された重複下垂体の1例

A case of duplication of the pituitary gland found by complaint of precocious puberty

重複下垂体（duplication of the pituitary gland：DPG）は先天性に下垂体を2つ有する極めてまれな疾患である。今回我々は，思春期早発症を主訴に発見された重複下垂体の1例を経験したため報告する。

We experienced a case of duplication of the pituitary gland（DPG）in an 8–year–old girl who presented with early onset of puberty. DPG is a rare disorder that has been reported in only about 50 cases. DPG is associated with a high rate of median structural abnormalities such as cleft palate and pharyngeal tumors, which are collectively referred to as DPG–plus syndrome. It can be fatal due to oral malformations, but otherwise endocrinologic manifestations, such as precocious puberty, can be problematic. It is considered necessary to search for a DPG when finding a median structural abnormality.