左房に発生した未分化多型肉腫の1例

Primary Cardiac Undifferentiated Pleomorphic Sarcoma in the Left Atrium：Report of a Case

はじめに　原発性心臓悪性腫瘍は発生頻度が低いが，予後は不良である．中でも未分化多型肉腫（UPS）は体幹・四肢軟部組織・長管骨などに好発する軟部肉腫で，心臓原発例の報告は非常にまれである．われわれは，左房に発生したUPSの1例を経験したので報告する．

A rare case of primary cardiac undifferentiated pleomorphic sarcoma （UPS） is reported. A 77-year-old female was admitted to the authors’ hospital with complaints of palpitation and dyspnea on effort. Echocardiography revealed a mobile tumor arising from the atrial septum of the left atrium. The tumor obstructed the mitral valve and the patient experienced acute heart failure. Emergent open-heart surgery was performed to resect the tumor. Although she was discharged from hospital on postoperative day 14 in a satisfactory condition, local recurrence in the left atrium was observed 16 months after surgery. Repeated tumor resection was performed, and histological examination confirmed UPS. The patient did not agree to undergo chemotherapy or radiation therapy and died of local recurrence 27 months after the first surgery.