末梢肺野に発生した扁平上皮腺上皮性混合型乳頭腫の1例

Mixed Squamous Cell and Glandular Papilloma in the Peripheral Lung：Report of a Case

はじめに　乳頭腫は通常喉頭から上気道内に多発性に発生するまれな良性上皮性腫瘍であり，特に肺癌との鑑別が問題となる．われわれは，肺癌が疑われた末梢肺野発生の孤立性扁平上皮腺上皮性混合型乳頭腫の1例を経験したため報告する．

Pulmonary papillary tumors are usually occur in the upper respiratory tract, and solitary papilloma in the peripheral lung are extremely rare. Lung papillomas sometimes show the elevation of tumor marker or F18-fluorodeoxyglucose （FDG） uptake, and are difficult to distinguish from lung carcinoma. Here we report a case of mixed squamous cell and glandular papilloma in the peripheral lung. An 85-years-old man without smoking history had been presented with an 8-mm nodule in right lower lobe in chest computed tomographic （CT） 2 years before. Since the diameter of the nodule increased to 12 mm, and positron emission tomography （PET） revealed an abnormally increased FDG uptake in the mass （SUVmax 4.61）. StageⅠA2 lung cancer （cT1bN0M0） was suspected and wedge resection of the lung to make a definitive diagnosis and for treatment was performed. The definite pathological diagnosis was mixed squamous cell and glandular papilloma.