The Japanese Journal of Thoracic Surgery Volume 71, Issue 7 (July 2018)
Japanese

p40 Negative Basaloid Squamous Cell Carcinoma of the Lung;Report of a Case Ryunosuke Maki 1 , Shintaro Sugita 1 , Yusuke Ono 1 , Masahiro Miyajima 1 , Makoto Tada 1 , Yuki Takahashi 1 , Taijirou Mishina 1 , Atsushi Watanabe 1 1Department of Thoracic Surgery, Sapporo Medical Universiry Keyword: lung cancer , basaloid squamous cell carcinoma , immunostaining , p40 , squamous cell carcinoma pp.547-550
Published Date 2018/7/1
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Immunohistochemical staining is important for the differential diagnosis of basaloid squamous cell carcinoma(BSC)and other similar carcinomas, such as small-cell carcinomas and large-cell neuroendocrine carcinomas. p40 is a useful marker of squamous cell carcinoma that can be used for the diagnosis of BSC. We present the case of a 64-year-old man who was referred to our hospital for investigation of an abnormal shadow revealed on chest radiography. Computed tomography(CT)revealed a 16×11 mm nodule in the left lung(S1+2), and a thoracoscopic left upper lobectomy was performed. Histologically, lobular pattern with peripheral palisading was observed and the immunohistochemical staining revealed the tumor cells to be positive for p63 and negative for both p40 and neuroendocrine markers, leading to the diagnosis of BSC.


© Nankodo Co., Ltd., 2018

基本情報

24329436.71.07.jpg
胸部外科
71巻7号 (2018年7月)
電子版ISSN 2432-9436 印刷版ISSN 0021-5252 南江堂

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