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Probable Immunoglobulin G4 (IgG4)-related Periaortitis Requiring Differentiation from Mediastinal Tumor Yoshiki Chiba 1 , Wataru Arai 1 , Miho Ohkawa 1 , Osamu Tada 1 , Ryunosuke Maki 1 , Taijiro Mishina 1 , Masahiro Miyazima 1 , Atsushi Watanabe 1 , Shintaro Sugita 1 1Department of Thoracic Surgery, Sapporo Medical University Keyword: probable immunoglobulin G4 (IgG4)-related periaortitis , mediastinal tumor , Behçet’s disease , steroid pp.108-111
Published Date 2021/2/1
DOI https://doi.org/10.15106/j_kyobu74_108
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A 42-year-old man with a history of suspected of Behcet’s disease underwent oral steroid treatment. During follow-up, chest X-ray revealed an abnormal shadow of the mediastinum. Chest computed tomography (CT) showed a circumferential tumor around the descending thoracic aorta. Enhanced CT showed a lowly and uniformly enhanced tumor at delay phase. A mediastinal tumor was suspected, which prompted a biopsy of the periaortic tumor by video-assisted thoracic surgery (VATS). Histopathological diagnosis showed numerous immunogloblin G4 (IgG4)-positive plasma cells suggesting the possibility of IgG4-related periaortitis. However, based on the diagnostic criteria, the case was comprehensively diagnosed as probable IgG4-related periaortitis, steroid treatment may have affected blood IgG4-positive cells and tissues.


© Nankodo Co., Ltd., 2021

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電子版ISSN 2432-9436 印刷版ISSN 0021-5252 南江堂

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