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Non-motor symptoms in Parkinson's disease patients during perioperative period of deep brain stimulation surgery: A five-cases study Atsuya Sato 1,3 , Taku Ochiai 2 , Tomio Kubota 3 , Toshiyuki Ishioka 3 1Department of Occupational Therapy, School of Rehabilitation, Tokyo Professional University of Health Sciences (Former: Department of Rehabilitation, Sanai Hospital) 2Ochiai Neurological Clinic 3Graduate Course of Health and Social Services, Graduate School of Saitama Prefectural University Keyword: パーキンソン病 , 認知機能 , せん妄 , 脳深部刺激療法 , 周術期 , Parkinson's disease , Cognitive function , Delusion , Deep Brain Stimulation , Perioperative period pp.747-755
Published Date 2021/12/15
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 To examine the characteristics of non-motor symptoms in patients with Parkinson's disease (PD) during the perioperative period of deep brain stimulation (DBS), we investigated cognitive functions and behavioral symptoms in five PD patients who underwent DBS to determine the target site via experimental stimulation of the subthalamic nucleus (STN) and the globus pallidus internus (GPi). The results showed a significant decrease in the phonemic verbal fluency task performance involving inhibition of habitual responses only during stimulation of the STN compared to before surgery, and delirium-like behavioral symptoms were observed in 4 of 5 patients after surgery. These results suggest the need for occupational therapy for perioperative PD patients with DBS that considers motor symptoms and non-motor symptoms, including behavior management in the ward.


Copyright © 2021, Japanese Association of Occupational Therapists. All rights reserved.

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電子版ISSN 印刷版ISSN 0289-4920 日本作業療法士協会

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