The relationship between behavioral and psychological symptoms of dementia (BPSD) and the autonomic nervous system in dementia patients Daisuke Kimura 1 , Masako Notoya 2 , Aiko Imai 3 , Taro Ohtoshi 1 1Department of Occupational Therapy, Faculty of Health Sciences, Kansai University of Health Sciences(Former affiliation; Kansai University of Welfare Sciences) 2Department of Speech and Hearing Sciences and Disorders, Faculty of Health and Medical Sciences, Kyoto Gakuen University 3Faculty of Care and Rehabilitation, Seijoh University Keyword: 自律神経 , 認知症 , BPSD , Autonomic nervous system , Dementia pp.377-384
Published Date 2018/8/15
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 This study aimed to examine the feasibility of predicting behavioral and psychological symptoms of dementia (BPSD) using heart rate variability analysis to measure autonomic nerve activity. This paper also examines BPSDs that are related to autonomic balance. Thirty-five elderly individuals with confirmed dementia were assessed, and BPSD was measured using the Neuropsychiatric Inventory (NPI). Autonomic nerve activity was measured with TAS9VIEW. For analysis, the subjects were separated into two groups: those split both above and those below the median value of the NPI data. A receiver operating characteristic curve was prepared by measuring the area under the curve in order to assess the usefulness of measuring autonomic nerve activity. Next, low to high frequency ratios (LF/HF) were used to classify the subjects into two additional groups: a sympathetic dominant group and a parasympathetic dominant group. The NPI scores between these two groups were compared, and BPSD was found to be associated with Total power (TP), HF, and LF. When parasympathetic nerve activity was dominant, the NPI total score was found to be significantly higher than average.

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電子版ISSN 印刷版ISSN 0289-4920 日本作業療法士協会