パーキンソン病患者における日中身体活動量の活動強度別の特徴および歩数との関連性

Characteristics of physical activity and their relevance to step number in patients with Parkinson's disease

要旨：本研究はパーキンソン病（以下，PD）患者の1日・時間帯別身体活動量における活動強度別（低強度，中強度以上）低下の特徴，中強度以上の活動時間と歩数との関連性を明らかにすることを目的とした．自立歩行可能な地域在住PD患者35名を対象とし，3軸加速度計にて各活動強度時間と歩数を計測しコントロール群と比較検討した結果，活動強度時間において，PD群が低い値を示した（p＜0.001）．またPD群の中強度以上の活動時間は歩数と高い相関関係を認め（R＝0.810，p＜0.001），コントロール群との平行性も保たれた（p＝0.512）．自立歩行可能なPD患者も健常者に比して身体活動量低下が明らかであり，PD患者は病初期から活動量向上のための対策が必要である．

　This study aimed to clarify characteristics of daily physical activity in patients with Parkinson's disease (PD), and to evaluate relations between Moderate to Vigorous Physical Activity (MVPA) and number of steps. This study included 35 PD patients and 70 neurologically normal control individuals. The amount of physical activity was measured using a 3-axis accelerometer. The average time of daily physical activity was analyzed in terms of intensity of physical activity and number of steps. As a result, the PD group showed lower values in all physical activities in terms of intensity (p <0.001). In addition, the time of medium intensity of the PD group showed a statistically significant positive correlation with the number of steps (R = 0.810, p <0.001), and parallelism with the control group was also maintained (p = 0.512). The results showed decreased physical activity in PD patients compared with that of the control group, although all PD patients participating in this study were in the early stages of the disease and independent. Thus, any intervention which increases physical activity is essential for early stage PD patients.