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The inhibition function in verbal fluency of patients with Alzheimer's disease Hirofumi Ouchida 1 , Ikuyo Fujita 2 1Department of Speech and Hearing Sciences, School of Health Sciences at Fukuoka, International University of Health and Welfare 2Graduate School of Health and Welfare Sciences, International University of Health and Welfare Graduate School Keyword: アルツハイマー病 , 抑制機能 , 語流暢性課題 , Alzheimer's disease , inhibition function , verbal fluency pp.155-163
Published Date 2017/9/15
DOI https://doi.org/10.11477/mf.6001200135
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 The purpose of this study is to examine inhibition in language processing in patients with Alzheimer's disease (AD) while they are doing verbal fluency tasks. The participants were 13 patients with AD and 13 healthy elderly controls. Semantic fluency (stationery, sports, fruits) and phonemic fluency (a, ki, si) tasks were presented, each with restricted recall and simple recall conditions. In the restricted recall, subjects were asked to exclude from their answers 'stationery used for cutting', 'water sports', 'purple fruits', and '5-kana words', respectively, thus restricting the range of allowable responses. Results showed that although there was no difference between the performance on restricted recall and unrestricted recall in the control group, the performance on restricted recall was significantly lower than that on simple recall in the AD group. In the tasks for restricted recall of semantic fluency, the AD group produced significantly more disallowed words than the control group. They also erroneously produced more words that are semantically related to the preceding responses in phonemic fluency tasks than the control group. Overall, these results suggest that inhibition in language processing is reduced in patients with AD.


Copyright © 2017, Japanese Association of Speech-Language-Hearing Therapists. All rights reserved.

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電子版ISSN 印刷版ISSN 1349-5828 日本言語聴覚士協会

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