Minimal invasiveness and patients'quality of life after laparoscopic surgery for advanced colorectal cancer Hirotoshi HASEGAWA 1 , Yoshiyuki ISHII 1 , Takashi ENDO 1 , Hiroki OCHIAI 1 , Shigeki ONOUCHI 1 , Teppei SAKOTA 1 , Shun IMAI 1 , Yuko KITAGAWA 1 1Department of Surgery, Keio University School of Medicine Keyword: 低侵襲性 , quality of life , 腹腔鏡下大腸切除術 pp.61-65
Published Date 2008/2/15
DOI https://doi.org/10.11477/mf.4426100148
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 We describe the minimal invasiveness and patients'quality of life after laparoscopic surgery for colorectal cancer. We conducted a randomised controlled trial comparing laparoscopic with open surgery for advanced colorectal cancer, and measured the serum level of interleukin-6, natural killer cell activity together with the serum level of C-reactive protein. There were no differences between the laparoscopic and open groups in terms of interleukin-6 level and natural killer cell activity. However, the serum levels of C-reactive protein on postoperative day 1 and 4 were significantly lower in the laparoscopic than in the open group.

 Large randomised controlled trials(COST, CLASICC, COLOR)included the evaluation of the quality of life after surgery. In one of the studies, a better quality of life after laparoscopic surgery was reported at early phase but the difference was of little clinical value, and no difference was found at 3 months postoperatively.

Copyright © 2008, JAPAN SOCIETY FOR ENDOSCOPIC SURGERY All rights reserved.


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