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The physiology of cardiopulmonary resuscitation Hidehiko TOKUNAGA 1 , Jumpei TSUKUDA 2,3 1Department of Critical Care Medicine, General Internal Medicine/Emergency Medicine Nerima Hikarigaoka Hospital 2Emergency Department, Thomas Jefferson University 3Emergency and Critical Care Medicine St. Marianna University School of Medicine pp.317-329
Published Date 2022/4/1
DOI https://doi.org/10.11477/mf.3102200969
  • Abstract
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In 2018, approximately 130,000 adults in Japan suffered out-of-hospital cardiac arrest. About 25,000 events were witnessed with overall survival averaging 13.9% after their initial hospitalization and 9.1% with good neurological status. These rates have been improving but are still not ideal. To obtain improved survival and neurological function, high-quality cardiopulmonary resuscitation (CPR) and public use of automated external defibrillators (AEDs) are important keys shown in the Chain of Survival. High quality CPR is not adequate to maintain perfusion to vital organs such as the brain and heart compared with normal physiological status. Therefore, some patients develop severe brain damage even after return of spontaneous circulation. In this chapter, we will study the science of circulation and ventilation during CPR from the physiological standpoint as well as the potential of new CPR methods and devices.


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電子版ISSN 2186-7852 印刷版ISSN 1883-4833 メディカル・サイエンス・インターナショナル

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