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The physiology of hypoxic-ischemic encephalopathy Hidetaka SUZUKI 1 , Satoshi EGAWA 2,3 1Department of Emergency and Critical Care Medicine Japanese Red Cross Musashino Hospital 2Neurocritical Care Unit, TMG Asaka Medical Center 3Columbia University Irving Medical Center Neurological ICU pp.251-264
Published Date 2022/4/1
DOI https://doi.org/10.11477/mf.3102200963
  • Abstract
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The brain has a very high oxygen demand. Therefore, it can be damaged by hypoxia for a variety of reasons. The pathophysiology of each of the factors that regulate oxygen supply to the brain is described in detail. Of these, cerebral blood flow has the greatest impact on the prognosis of patients with hypoxic encephalopathy. The process by which neurons exposed to hypoxia are damaged is similar regardless of the cause, and it is hoped that new therapeutic approaches will be established in the future.


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電子版ISSN 2186-7852 印刷版ISSN 1883-4833 メディカル・サイエンス・インターナショナル

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