Biochemical markers of bone turnover Rika Kido 1 , Itsuro Endo 1 , Toshio Matsumoto 1 1Department of Medicine and Bioregulatory Sciences, The University of Tokushima Graduate School of Medical Sciences Keyword: 骨粗鬆症 , 骨質 , 骨形成 , 骨吸収 pp.1503-1508
Published Date 2011/12/15
DOI https://doi.org/10.11477/mf.1542102861
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Osteoporosis is defined by the Consensus Development Panel of National Institutes of Health in 2000 as a disorder characterized by compromised bone strength predisposing to an increased risk of fracture. Bone strength reflects the integration of bone density and bone quality, and both the density and quality of bone are influenced by bone turnover. Bone turnover can be evaluated by measuring its biochemical markers. Various bone turnover markers have been developed to assess bone resorption and bone formation. In this review, we outline the significance of bone turnover and how to use its markers appropriately.

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