化學療法により治癒したルードウィッヒ氏アンギーナの2例

　本症は頸部壞疽性蜂窠織硬結症と名付けられ，1838年Wilhelm Friedrich v. Ludwigによつて始めて記載されてから，所謂ルードウイツヒ氏アンギーナとして，諸家の幾多の業績が報告されその本態，原因，病理に關して，漸次解明される所となつて來た。又從來本症に對する治療法は口腔外切開が多く行われ，口腔内切開法はあまり行われておらない樣であつた。然し乍ら最近に於いては化學療法の進歩によりサルフア劑及びペニシリン等の抗生物質の併用により口腔内切開を行つて好結果を得たとの報告がある。

　吾々は最近，本症の2例に遭遇し，サルフア劑竝にペニシリンを投與する事により何ら切開を加える事なく，治癒せしめたので茲に報告し，諸賢の御批判を仰ぐ次第である。

　AKAIKE and HIRAYAMA report 2 cases of Ludwig's angina; both cases were effectively cured by chemotheraphy. The first case was a man aged 24 and the second a 16 years old boy. Excepting for inflammatory swelling of subligual salivary gland which presumably was brought on by presence of sialolith in the first case, there were no apparent cause for the onset of the disease in either of them. The regimen of treatment followed in the first case was intramuscular injections of 2.5 million units of penicillin in oil for 10 days supplemented by intravenous injections of 5cc 10% homosulfamin solution and oral administration of 60 grains sulfathiazol daily for 5 days. In the second in similar way 1.5 million units of penicillin in oil was supplemented by 5cc 10% thiasin intravenously with oral administration of 55 grains of salzol. The authors believe that use of chemotherapy is more advantageous in this disease in that it has enabled to shorten the courge to a greater extent in comparison to treatments with iucisions.