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Japanese

Carbamazepine Induced Hyponatremia Takanori INAMURA 1 , Hiroshi KUBA 1 , Takato MORIOKA 1 , Hiroshi MURATANI 1 , Mituteru MURAISHI 1 , Kei HISADA 1 , Masashi FUKUI 1 1Department of Neurosurgery, Neurological Institute, Faculty of Medicine, Kyushu University Keyword: carbamazepine , hyponatremia , syndrome of inappropriate antidiuretic hormone(SIADH) pp.85-87
Published Date 1999/1/10
DOI https://doi.org/10.11477/mf.1436902512
  • Abstract
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Carbamazepine (CBZ) is a drug which can induce the syndrome of inappropriate antidiuretic hormone(SIADH). Until 1980's, there were reports regarding CBZ-induced SIADH, but it is rarely reported thesedays. We here report two cases of CBZ-induced SIADH. Hyponatremia in these cases was rapidly im-proved by withdrawal of administration of CBZ. According to the previous reports, the rate of hyponatre-mia in patients receiving CBZ is not small. It ranges from 4.8% to 31%. As CBZ is frequently used for pa-tients with epilepsy and neuralgia, not only their blood CBZ concentration but also their serum Na levelshould be monitored.


Copyright © 1999, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1251 印刷版ISSN 0301-2603 医学書院

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