粥状動脈硬化性頸動脈病変と脳室周囲高信号域（PVH）の関連性

The Relationship between Extracranial Carotid Atherosclerosis in an Ultrasound Study and Periventricular Hyperintensity in MR Images

Ⅰ．緒言

　MR画像，特にT2強調画像やfluid attenuated in-version recovery（FLAIR）法で鋭敏に捉えられる側脳室周囲高信号域（periventricular hyper inten-sity：以下PVH）は，病理組織学的所見との対比から多くの異なる変化が含まれていることが示唆されおり，その成因には加齢，高血圧，特に虚血性病変の存在が関与するとされている^1,5,8,16）．その虚血性病変の成因に深く関与しているのが粥状動脈硬化であるが，PVHと粥状動脈硬化の関連を検討した報告は少ない．そこで，今回われわれは，頸動脈粥状動脈硬化を低侵襲で評価できる超音波断層法（B-mode法）を使用し，粥状動脈硬化とPVHとの関連を検討したので報告する．

We have evaluated the relationship between carotid atherosclerotic change and periventricular hyper intensity (PVH). PVH was studied in 66 cases with cerebral thrombosis, comparing them with another group of age-matched controls, which consisted of 29 cases with hypertension, diabetes, and hypercholesteremia. MRI (fluid attenuated in-version recovery) and B-mode carotid ultrasonography of each lesion were analyzed. Thrombosis lesions, compatible with neurological manifestation were divided into two types, cerebral cortical type (including centrum semiovale type) and small infarction in the deep subcortical type.