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The Efficacy of Prophylactic Administration of SBT/ABPC for Postoperative Infection in Neurosurgical Operations Koji IDOMARI 1 , Keiichi SAKAI 1 , Hisayoshi TAKASAWA 1 , Yosuke MIYAIRI 1 , Takehiro YAKO 1 , Takahiro MURATA 1 , Michio SAKAMOTO 1 , Junpei NITTA 1 , Kazuhiro HONGO 1 , Sigeaki KOBAYASHI 1 , Toshiki AOKI 2 , Satoshi KOBAYASHI 2 1Department of Neurosurgery, Shinshu University School of Medicine 2Department of Neurosurgery, Kenseikai Kobayashi Neurosurgical Hospital Keyword: antibiotic prophylaxis , MRSA(methicillin-resistant Staphylococcus aureus) , neurosurgery , SBT/ABPC , surgical site infection pp.1075-1080
Published Date 2002/10/10
DOI https://doi.org/10.11477/mf.1436902285
  • Abstract
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We investigated prospectively the efficacy of sulbactam sodium/ampicillin sodium (SBT/ABPC), which is a combina-tion drug of ampicillin and β-lactamase inhibitor, as a preventive drug against postoperative infection in the field of neurological surgery. One hundred and six patients were given SBT/ABPC as follows: Before anesthetic induction at surgery, 1.5g of SBT/ABPC was administrated by intravenous drip infusion, and further doses were continued at 12-hour intervals for 5 to 7 days. We assessed postoperative infection, type of surgery, duration of operation, and amount of hemorrhage.


Copyright © 2002, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1251 印刷版ISSN 0301-2603 医学書院

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