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Extracranial Metastasis of Glioblastoma to the Lung and Heart with a Histological Resemblance to Small Cell Carcinoma of the Lung : an autopsy case Nobuhiro HATA 1 , Toshiro KATSUTA 1 , Tooru INOUE 1 , Keisuke ARIKAWA 2 , Takafumi YANO 2 , Morishige TAKESHITA 3 , Toru IWAKI 4 1Department of Neurosurgery Clinical Research Institute, National Kyushu Medical Center Hospital 2Department of Internal medicene Clinical Research Institute, National Kyushu Medical Center Hospital 3Department of Pathology Clinical Research Institute, National Kyushu Medical Center Hospital 4Department of Neuropathology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University Keyword: glioblastoma , extracranial metastasis , N-CAM , primitive neuroectodermal tumor , small cell carcinoma of the lung pp.433-438
Published Date 2001/5/10
DOI https://doi.org/10.11477/mf.1436902041
  • Abstract
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An autopsy case of small cell glioblastoma, showing multiple extracranial metastases, is reported with special reference to histopathological differentiation from metastatic small cell carcinoma. Widely spread le- sions in the bilateral lungs were developed after an operation and chemo-radiotherapy for glioblastoma, and the lung lesions led to fatal respiratory failure. Postmortem examination revealed multiple tumors in the lung, lymph nodes, and the heart, as well as local invasion of the primary tumor to the dura, skull, and the scalp. The mechanism of extracranial metastasis of brain tumor is discussed.


Copyright © 2001, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1251 印刷版ISSN 0301-2603 医学書院

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