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特集 臨床脳神経外科医にとってのWHO脳腫瘍分類第5版
Ⅱ 成人悪性脳腫瘍
膠芽腫,IDH野生型
Glioblastoma, IDH-Wildtype
柴原 一陽
1
,
隈部 俊宏
1
Ichiyo SHIBAHARA
1
,
Toshihiro KUMABE
1
1北里大学医学部脳神経外科
1Department of Neurosurgery, Kitasato University School of Medicine
キーワード:
膠芽腫
,
IDH野生型
,
WHO脳腫瘍分類第5版(WHO 2021分類)
,
glioblastoma
,
IDH-wildtype
,
5th edition of the WHO Classification of Tumours of the Central Nervous System Tumours
Keyword:
膠芽腫
,
IDH野生型
,
WHO脳腫瘍分類第5版(WHO 2021分類)
,
glioblastoma
,
IDH-wildtype
,
5th edition of the WHO Classification of Tumours of the Central Nervous System Tumours
pp.821-828
発行日 2023年9月10日
Published Date 2023/9/10
DOI https://doi.org/10.11477/mf.1436204823
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- 参考文献 Reference
Point
・WHO脳腫瘍分類第5版で膠芽腫の定義が変更となった.
・MRI画像から膠芽腫と確定診断することは必ずしも容易ではない.
・膠芽腫治療におけるがん遺伝子パネル検査および分子標的薬の役割は期待できる.
The 5th edition of the WHO Classification of Central Nervous System Tumours(WHO2021)emphasizes the importance of molecular classification. A significant update was that glioblastoma IDH-mutant from WHO2016 was renamed and classified as astrocytoma IDH-mutant WHO grade 4 in WHO2021. This review describes the current updates to the glioblastoma classification, and discusses the essential knowledge regarding daily practice, especially for young neurosurgeons.
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