Posterior Subthalamic Area, Pallidothalamic Tract, and Pedunculopontine Nucleus:Deep Brain Stimulation Targets for Parkinson's Disease and Essential Tremor Hiroki TODA 1 , Daisuke KAMBE 2 , Atsushi SHIMA 2 , Namiko NISHIDA 1 , Nobukatsu SAWAMOTO 3 1Department of Neurosurgery, Kitano Hospital, Tazuke Kofukai Medical Research Institute 2Department of Neurology, Kyoto University Graduate School of Medicine, Kyoto University Graduate School of Medicine 3Department of Human Health Sciences, Kyoto University Graduate School of Medicine Keyword: 脳深部刺激療法 , 後腹側視床領域 , Forel H1野 , 淡蒼球視床路破壊術 , 脚橋被蓋核 , deep brain stimulation , posterior subthalamic area , field H1 of Forel , pallidothalamic tractotomy , pedunculopontine nucleus pp.820-828
Published Date 2021/7/10
DOI https://doi.org/10.11477/mf.1436204460
  • Abstract
  • Look Inside
  • Reference

 This article reviews the stereotactic targets in the posterior subthalamic area(PSA), fields H1/H2 of Forel(pallidothalamic tract), and the pedunculopontine nucleus(PPN)to complement the preceding articles on stereotactic and functional neurosurgery for movement disorders in the present issue of No Shinkei Geka.

 Two regions within the subthalamus, the PSA and fields H1/H2 of Forel, are the revisited stereotactic targets to treat movement disorders. Currently, the PSA is often utilized to treat essential tremor and various types of tremor. Fields H1/H2 of Forel are investigated as a target for magnetic resonance-guided focused ultrasound to treat motor symptoms and motor complications in patients with Parkinson's disease. For the past twenty years, the PPN has been investigated to treat refractory gait freezing and fall in patients with Parkinson's disease. These revisited and novel targets may be utilized as substitutes and complements for the present standard stereotactic targets.

Copyright © 2021, Igaku-Shoin Ltd. All rights reserved.


電子版ISSN 1882-1251 印刷版ISSN 0301-2603 医学書院