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Neuronal Intranuclear Inclusion Disease(NIID) Aki SATO 1 1Department of Neurology, Niigata City General Hospital Keyword: 核内封入体 , U-fiber , 皮膚生検 , intranuclear inclusion , skin biopsy pp.419-424
Published Date 2021/3/10
DOI https://doi.org/10.11477/mf.1436204408
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 Neuronal intranuclear inclusion disease(NIID)is a progressive neurodegenerative condition characterized by eosinophilic hyaline intranuclear inclusions in neuronal and other somatic cells. Since 2011, when skin biopsy was proven to be a diagnostic tool, the incidence of NIID has been increasing. Its symptoms include dementia, muscle weakness, and sensory or autonomic disturbance. MRI shows hyperintense lesions of the subcortical white matter, especially on the U-fiber. These findings persist and continue to worsen for years.


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電子版ISSN 1882-1251 印刷版ISSN 0301-2603 医学書院

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