Neurological Surgery No Shinkei Geka Volume 45, Issue 1 (January 2017)

A Case of Intracranial Localized Castleman's Disease Mimicking Convexity Meningioma Keisuke OZONO 1 , Takashi FUJIMOTO 1 , Makoto HIROSE 2 , Ichiro KAWAHARA 2 , Kazuyoshi UCHIHASHI 3 1Department of Neurosurgery, Nagasaki University Hospital 2Department of Neurosurgery, Nagasaki Rosai Hospital 3Department of Pathology and Oncology, University of Occupational and Environmental Health Keyword: Castleman's disease , intracranial tumor , localized type , meningioma , perifocal edema pp.39-45
Published Date 2017/1/10
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 A 68-year-old man presented with abnormal behavior and Todd's paralysis on the right side after having taken a bath. Computed tomography and magnetic resonance imaging revealed a tumor mimicking convexity meningioma that had a perifocal edema, although its mass was not very large. The patient underwent surgery, and full recovery was achieved following a total removal of the lesion. Pathohistological examination demonstrated an intermediate type of Castleman's disease. The final diagnosis was intracranial localized Castleman's disease because the results of the full physical examination and laboratory analyses were normal.

 Castleman's disease is a rare lymphoproliferative disorder of unknown etiology. Moreover, intracranial involvement is very rare. In cases of intracranial meningeal tumors with perifocal edema, we should take this disease into consideration in the differential diagnosis.

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Neurological Surgery 脳神経外科
45巻1号 (2017年1月)
電子版ISSN 1882-1251 印刷版ISSN 0301-2603 医学書院