Two Cases of Cerebral Infarction due to Focal Irradiation for Glioma in Adults Noriaki MINAMI 1 , Katsu MIZUKAWA 1 , Hirofumi IWAHASHI 1 , Hiroaki NAGASHIMA 1 , Kazuhiro TANAKA 1 , Takashi SASAYAMA 1 , Kohkichi HOSODA 1 , Naritoshi MUKUMOTO 2 , Ryohei SASAKI 2 , Eiji KOHMURA 1 1Department of Neurosurgery, Kobe University Graduate School of Medicine 2Division of Radiation Oncology, Department of Radiology, Kobe University Graduate School of Medicine Keyword: radiation-induced vasculopathy , focal irradiation , complication , glioma pp.344-351
Published Date 2015/4/10
DOI https://doi.org/10.11477/mf.1436203018
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 Radiation-induced vasculopathy is a complication of radiation therapy. Most reports regarding post-irradiation ischemic stroke with intracranial tumors are restricted to pediatric cases. Here we report two adult cases of delayed brain infarction due to anterior and middle cerebral artery stenosis or occlusion seemingly caused by focal radiation therapy for malignant glioma. Although radiation-induced ischemic stroke in adults is relatively uncommon, it is possible that the morbidity rate of radiation-induced stroke in malignant glioma patients will increase with prolonged survival due to advances in therapy. Therefore, regular evaluation of intracranial vasculature following radiation therapy is necessary.

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