髄膜腫術後再発例の検討

Analysis of Recurrences of Meningiomas Following Neurosurgical Resection

I．はじめに

　髄膜腫は全ての原発性頭蓋内腫瘍の約21.5％^17）を占めており，一般に良性で発育は緩徐であり，外科的全摘出により治癒が可能といわれている．しかし，2.3％から30％の再発率が報告されており^3），外科的摘出後も少なからず再発が生じているのが現状である．今回われわれは，髄膜腫の再発例に関してretrospectiveに検討し，再発に関与する因子を臨床像および組織学的見地より検討を加えた．

A clinical and pathological study of 124 surgically treated patients with intracranial meningiomas was car-ried out to evaluate factors influencing recurrence. The patients ranged in age from 8 years to 75 years. Thirty-five (28.2%) were males and 89 (71.8%) were females. Recurrences occurred in 18 patients, once in eleven, twice in six, four times in one. The period from first surgery to recurrence ranged from 5 months to 84 months (mean 29.9 months). Age, sex, site of tumor, surgical grading, and histology were selected as analy-tic factors. Simpson's classification was used as surgical grading.