高ピーク出力炭酸ガスレーザーとYAGレーザーの単独および同軸複合照射に関する研究—第2報 脳微細血管への亜急性期の影響

Experimental Study of Single and Combined Coaxial Exposure by High-peaked Pulse Wave Form CO2 and Nd: YAG Laser on the Brain: Effect on the brain microvasculature at the subacute stage

I．はじめに

　最近，各種外科手術におけるレーザーの有用性が認識されるようになり，脳神経外科領域において今後も多くの可能性を秘めていると考えられる．われわれはこれまでに高ピーク出力炭酸ガスレーザー（high-peaked pulsewave form CO₂laser，以下PWと略す）と，Nd：YAGレーザー（以下YAGと略す）の単独および同軸複合照射の脳組織への急性期の影響について動物実験を行い発表してきた^2-5）．今回PW, YAGの単独および同軸複合照射48時間後の脳組織への影響について微小血管構造および組織学的所見から検討した．

The effect of single or combined coaxial exposure by Nd : YAG and CO₂ (pulse wave) laser on the brain at the subacute stage was examined in experimental ani-mals. Soft X-ray microangiography and histological ex-amination of the brain were performed 48 hours after laser exposure. The lasers in this study were pulse wave form CO₂ of 2, 4 and 8 watts and YAG lasers of 10, 20 and 40 watts, employed separately or simul-taneously using 130 YZ of Nihon Infrared Industries Company. Japanese white rabbits were anesthetized with pentobarbital. Bilateral fronto-parietal craniecto-mies were made, and the dura was removed.