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Marked Effect of Furosemide and Hypertoni Saline in the Treatment of SIADH after Head Injury Hideaki IWASA 1 , Takeshi YAMADA 1 , Noboru NAKAHA 1 , Hiroshi SHIMABUKURO 1 , Sohji SHINODA 1 , Itsuo INDEI 1 , Naoshi YAMADA 1 , Fumiaki SATO 1 , Toshikazu SAITO 2 1Department of Surgical Neurology, Jichi Medical School 2Deptartment of Endocrinology & Metabolism, Jichi Medical School Keyword: SIADH , Head injury , Hyponatremia , Hypertonic saline , Furosemide pp.651-655
Published Date 1984/4/10
DOI https://doi.org/10.11477/mf.1436201849
  • Abstract
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A case of SIADH after head injury was encounter-ed and treated successfully with furosemide and hyper-tonic saline. 250 mg of furosemide was given twiceat two hours' interval. The dose of 2.5% saline for theinfusion was calculated according to the excretion ofsodium in the urine collected during this period. The level of serum sodium quickly rose from 113mEq/1 to 137 mEq // in 33 hours. The consciousnessof the patient returned to normal.

The problems of quick correction of hyponatremiaincluding the central pontine neurolysis were discussed


Copyright © 1984, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1251 印刷版ISSN 0301-2603 医学書院

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