全身転移を示した頭蓋内Germinomaの1例

A Case of Intracranial Germinoma with Multiple Remote Metastases

Ⅰ．はじめに

　原発性頭蓋内腫瘍の頭蓋外転移は稀なものであり，間葉性腫瘍，小脳髄芽腫，膠芽腫等がその報告の大部分を占める．germinomaの頭蓋外転移は，髄腔内播種性転移を除くと，その遠隔転移は極めて稀であり，これまで8例の報告を見るのみである．このような1例を経験し剖検の機会を得たので報告する．

A case of suprasellar germinoma with multiple remote metastases was reported including its autopsy findings. Several series of radiation therapy and prolonged steroid administration were considered to be causes of immunosuppression bringing about such metastases.

A 29-year-old man had undergone a suprasellar germinoma removal and 5,200 rad of postoperative local irradiation at a university hospital 5 months prior to the admission to our clinic. A walnut-sized left cerebellopontine angle mass was subtotally extirpated by us, which proved to be germinoma. Total dosis of 5,550 rad with linear was applied locally to the operated site.