脳動脈瘤手術後の尿崩症の検討—特にADH, Aldosterone分泌について

Diabetes Insipidus after Surgery of Intracranial Arterial Aneurysms: With Special Reference to the Human ADH and Aldosterone Secretion

Ⅰ．緒言

　Landoltら^2）（1972）によれば脳動脈瘤手術後に水電解質の異常が44％にも生ずると報告されており，術後管理上重大な問題である，今回は脳動脈瘤手術後の尿崩症（以下DIと略す）を取り上げ，その病像について種々検討し，また特に血漿ADH, Aldosteroneを術前後にわたってRadioimmunoassayにより測定し，興味ある知見を得たので，ここに報告し，若干の考察を加える．

The cases of diabetes insipidus (DI) after surgery of intracranial aneurysms were reported and discussed.

1. Of 112 patients operated on for intracranial arterial aneurysm (microsurgical approach), four patients (3.6% showed DI in the postoperative period. In 3 cases of these 4, the aneurysms located on the anterior com municating artery and the remaining one was the posterior inferior cerebellar artery.