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Japanese

Hypernatremia due to Hypothalamic tumor: ADH response to changes in plasma osmolality Keigo MATSUMOTO 1,2 , Kiyohito KAKITA 1 , Seishi FUKUMA 1 1Department of Neurosurgery, Kyoto First Red Cross Hospital Keyword: Hypernatremia , Hypothalamic syndrome , Hypothalamic tumor , Plasma ADH pp.267-271
Published Date 1989/3/10
DOI https://doi.org/10.11477/mf.1436202790
  • Abstract
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A case of a patient with the syndrome of chronic hypernatremia and hypodispia due to hypothalamic tumor was studied to evaluate the change of ADH res-ponse to plasma osmolality during the clinical course.

A 23-year-old man was admitted for investigation of anorexia, hypodipsia and gait disturbance. Examination showed memory disturbance and generalized muscle weakness. Investigation showed marked hypernatremia (177mEq/l) and hypopituitarism. Water loading test showed that ADH was not stimulated by hyperosmolal-ity but continued to be secreted at a more or less con-stant level approximating normal basal state.


Copyright © 1989, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1251 印刷版ISSN 0301-2603 医学書院

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