雑誌文献を検索します。書籍を検索する際には「書籍検索」を選択してください。

検索

書誌情報 詳細検索 by 医中誌

Japanese

Primary Yolk Sac Tumor in the Cerebellar Vermis. Case Report Taigen NAKAMURA 1 , Masayuki KANAMORI 1 , Yukihiko SONODA 1 , Mika WATANABE 2 , Toshihiro KUMABE 1 , Teiji TOMINAGA 1 1Department of Neurosurgery,Tohoku University Graduate School of Medicine 2Department of Pathology,Tohoku University Hospital Keyword: germ cell tumor , yolk sac tumor , cerebellar vermis pp.173-177
Published Date 2009/2/10
DOI https://doi.org/10.11477/mf.1436100891
  • Abstract
  • Look Inside
  • Reference

 A 2-year-old boy presented with gait disturbance and limb ataxia. T1-weighted magnetic resonance (MR) imaging with gadolinium-diethylenetriaminepenta-acetic acid administration showed a heterogeneously enhanced mass lesion with a cystic component in the cerebellar vermis. The minimum apparent diffusion coefficient value of the lesion was 1.96×10-3mm2/sec, and 1H-MR spectroscopy showed elevated choline and lipid peaks, and decreased N-acetyl aspartate peak. The tumor was totally resected, and the histological diagnosis was yolk sac tumor. Consistent with this diagnosis, a-fetoprotein levels in the serum and cerebrospinal fluid were 7,094ng/ml and 22.3ng/ml, respectively. 18F-fluorodeoxyglucose-positron emission tomography, and thoracic, abdominal, and pelvic computed tomography showed no abnormal lesions, excluding the possibility of metastatic yolk sac tumor from an extracranial lesion. The patient received chemotherapy consisting of ifosfamide, cisplatin, and etoposide, and had not relapsed at 6 months after resection. Germ cell tumors rarely develop in the posterior fossa. This case suggests that yolk sac tumor could develop in the cerebellar vermis.


Copyright © 2009, Igaku-Shoin Ltd. All rights reserved.

基本情報

電子版ISSN 1882-1251 印刷版ISSN 0301-2603 医学書院

関連文献

もっと見る

文献を共有