脳転移を来した子宮平滑筋肉腫の1例

Leiomyosarcoma of the Uterus Metastatic to Brain

Ⅰ．は じ め に

　子宮肉腫は子宮悪性腫瘍の約1～5％を占め，このうち子宮平滑筋肉腫は約25％を占める比較的稀な腫瘍である^2,6,9,10)．子宮平滑筋肉腫は極めて悪性度の高い腫瘍で，肺，肝臓，腹腔内に高率に転移を起こすが脳転移は極めて稀であるとされ^8,10)，現在までに13例の文献報告例があるにすぎない^1-10)．今回，われわれは子宮平滑筋肉腫の脳転移例に対し，今までに報告例のないガンマナイフ治療を行い比較的良好な経過が得られた症例を経験したので報告する．

A case of 52-year-old female presented with dysarthria and paresis of right upper extremity 3 years after an operation and chemotherapy for uterine leiomyosarcoma. Magnetic resonance imaging showed an enhanced mass in the left corona radiata. Brain biopsy was carried out and pathological examination of the specimen showed features of a leiomyosarcoma. Uterine leiomyosarcoma is an uncommon tumor and its metastasis to the brain is rare. Only 13 other cases have been published. The patient underwent γ-knife therapy and obtains good quality of life.