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Japanese

L-Dopa induced dyskinesia Takashi Ohmoto 1 , Yuzo Matsumoto 1 , Shigeo Nakamura 1 1Department of Neurological Surgery, Okayama University Medical School pp.23-37
Published Date 1981/2/10
DOI https://doi.org/10.11477/mf.1431905247
  • Abstract
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 L-Dopa induced dyskinesias were developed in 30 (54.5%) out of 55 patients with Parkinsonism during chronic treatment of L-Dopa combined with MK-486. The dyskinesias consisted of buccolingual movements and choreo-athetoid movements of extremities. They seemed to be dosedependent because they were improved following reduction in dosage. Plasma dopa concentration was paralleled with the clinical status , and dyskinesias were observed at the peak dose in most patients. Sixteen out of 35 patients who had had ventrolateral thalamotomy developed dyskinesias of extremities on the side ipsilateral to the thalamotomy.


Copyright © 1981, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1243 印刷版ISSN 0001-8724 医学書院

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