Histological and Histochemical Studies on the Eosinophilic Intranuclear Inclusions of the Pigment Cells of the Substantia Nigra：A New Type of Senile Change

　Shiraki et al (personel communication) haverecently described eosinophilic inclusions innuclei of pigment cells of the substantia nigraof various central nervous system diseases, anddiscussed, to some extent, their significance. Both histological and histochemical studies werecarried out as to these intranuclear inclusionsin a series of 120 cases of various centralnervous system diseases.

　The results obtained were summarized asfollows：