Relapse of herpes simplex encephalitis and meningitis Hideyuki HASHIGUCHI 1 , Sadatoshi TSUJI 1 , Hiroshi SHOJI 2 1Department of Neurology, University of Occupational and Environmental Health 2First Department of Internal Medicine, Kurume University School of Medicine Keyword: 再発性単純ヘルペス脳炎 , 再発性単純ヘルペス髄膜炎 , Mollaret髄膜炎 , Polymerase chain reaction pp.82-93
Published Date 1999/2/10
DOI https://doi.org/10.11477/mf.1431901028
  • Abstract
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In recent years, the relapse of herpes simplex encephalitis (HSE) has been reported after conventional acyclovir or vidarabine therapy. The relapsing episode appeared to have occured within 2-4 weeks of cessation of successful antiviral therapy. Pediatric patients of HSE with cortical damage often relapsed with a movement disorder, but it might be a late symptom of the initial viral illness. In the older patients, men have been more often affected than women. The pathogenesis is still unclear.

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