雑誌文献を検索します。書籍を検索する際には「書籍検索」を選択してください。

検索

書誌情報 詳細検索 by 医中誌

Japanese

Knock-out mice for genes related to myelinogenesis Nobuya FUJITA 1 1Department of Neurology, Brain Research Institute, Niigata University Keyword: ミエリン蛋白 , ミエリン脂質 , ノックアウトマウス pp.802-812
Published Date 1997/10/10
DOI https://doi.org/10.11477/mf.1431900996
  • Abstract
  • Look Inside

Myelin, a membrane characteristic of the nervous system, wraps around the nerve fibers and acts as an insulator to increase the velocity of nerve impulses. Although most biological membranes have a higher ratio of proteins to lipids, both CNS and PNS myelin is characterized by a high proportion of lipid (70%) and a low proportion of protein (30%). Two sphingolipids, galactocerebroside (GalC) and sulfatide, are the most typical of myelin. Krabbe disease and metachromatic leukodystrophy (MLD) involve abnormal degradation of these sphingolipids, respectively.


Copyright © 1997, Igaku-Shoin Ltd. All rights reserved.

基本情報

電子版ISSN 1882-1243 印刷版ISSN 0001-8724 医学書院

関連文献

もっと見る

文献を共有