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Neurotrophin synthesis for regeneration of brain damage Shoei FURUKAWA 1 1Department of Molecular Biology, Gifu Pharmaceutical University pp.957-965
Published Date 1995/12/10
DOI https://doi.org/10.11477/mf.1431900698
  • Abstract
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Neurotrophins are a family of nerve growth factor (NGF) -related proteins, including brain-derived neurotrophic factor (BDNF) , neurotrophin (NT) -3, NT-4/5 and NT-6. They act on various types of neurons of peripheral and central nervous system depending on the expression of their own high affinity receptors, trk gene products, Trk, TrkB and/or TrkC on the surface of neurons. They support neuronal survival and promote neuronal differentiation in immature stage of neurons. Furthermore, important roles for neuronal regeneration are thought to be involved among the actions of neurotrophins.


Copyright © 1995, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1243 印刷版ISSN 0001-8724 医学書院

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