Neural network of prefrontal cortex Masahiko Takada 1 , Shigehiro Miyachi 1 1Department of System Neuroscience, Tokyo Metropolitan Institute for Neuroscience, Tokyo Metropolitan Organization for Medical Research Keyword: 頭頂・側頭・後頭連合野 , 傍辺縁系連合野 , 運動関連領野 , 大脳基底核 , 小脳 pp.482-490
Published Date 2005/8/10
DOI https://doi.org/10.11477/mf.1431100065
  • Abstract
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The prefrontal cortex is located extensively in the anterior part of the frontal lobe and developed well in humans and non-human primates. In view of the fact that the prefrontal cortex receives and integrates large bits of diverse information from the parietal, temporal, and occipital association cortical areas(termed the posterior association cortex)and paralimbic association cortical areas and, in turn, sends such information to the primary motor cortex by way of multiple motor-related areas, it is most likely that the prefrontal cortex plays crucial roles in executive control of behavioral actions. The systems of inputs from the posterior and paralimbic association cortical areas to the prefrontal cortex are classified primarily into six groups. Cognitive signals derived from the prefrontal cortex are conveyed to the rostral motor-related areas to transform them into motor signals, which finally enter the primary motor cortex via the caudal motor-related areas. Moreover, it has been shown that the basal ganglia and the cerebellum have separate output channels toward the prefrontal cortex, thus indicating the possible existence of loop circuits linking these brain regions.

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